Analysis on standard treatment of 75 cases of severe organophosphorous pesticide poisoning
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摘要: 目的:探讨规范性治疗方案对急性有机磷农药中毒 (AOPP) 患者效果的评价。方法:收集我院2009-2012年间收治的78例AOPP患者和2013-2016年间收治的75例AOPP患者, 荟萃分析治疗经验教训, 针对性制定出优化治疗方案, 比较规范性治疗前后AOPP患者的胆碱酯酶活力恢复时间、意识恢复时间、气管拔管时间、平均住院日、并发症发生率及病死率。结果:规范性治疗组患者的胆碱酯酶活力恢复时间、机械通气时间、平均住院日、意识恢复时间、并发症发生率及病死率均明显比未实行规范性治疗组缩短。结论:规范抢救流程, 可明显降低AOPP患者的病死率, 缩短住院时间。Abstract: Objective: To evaluate the effect of standardized treatment regimen on patients with acute severe organophosphorus pesticide poisoning.Method: Seventy-eight patients with severe organophosphorus pesticide poisoning admitted to our hospital from 2009 to 2012 were collected to develop treatment programmes from the metaanalysis of treatment experiences and lessons learned, and compared the cholinesterase activity recovery time, consciousness recovery time, tracheal extubation time, average hospital day, complication incidence and mortality rate in patients with severe organophosphate poisoning before and after standardized treatment.Result: The recovery time of cholinesterase activity, mechanical ventilation time, average hospital day, consciousness recovery time, complication incidence and mortality rate in the standardized treatment group were all significantly shorter than those in the non-standardized treatment group.Conclusion: Normative rescue process can significantly reduce the mortality of AOPP patients and shorten the length of hospitalization
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