ICU病房常见致病菌细菌分布及耐药分析

李理; 白颖; 周宁

doi:10.13201/j.issn.1009-5918.2018.04.008

ICU病房常见致病菌细菌分布及耐药分析

- 北京积水潭医院重症医学科(北京, 100035)

详细信息

通讯作者: 白颖, E-mail:baiyingcn@sina.cn

中图分类号: R978

收稿日期: 2018-03-28

Surveillance and drug resistance on pathogenic bacteria in our hospital

- Department of ICU, Beijing Jishuitan Hospital, Beijing, 100035, China

More Information

Corresponding author: BAI Ying, E-mail: baiyingcn@sina.cn

Received Date: 28 March 2018

摘要

摘要: 目的: 了解我院ICU病房常见致病菌的流行状况及细菌耐药情况, 从而为指导临床合理使用抗菌药物提供依据。方法: 对我院2015-01-2017-12期间ICU病房送检的阳性标本致病菌情况和药敏试验结果, 进行回顾与分析。结果: 2015-2017年间病房共分离菌株834株, 其中革兰阳性菌占23.7%, 革兰阴性菌占72.1%。革兰阳性球菌中的金黄色葡萄球菌和表皮葡萄球菌仅对万古霉素、利奈唑胺、奎奴普丁/达福普汀敏感性高, 对克林霉素、青霉素和红霉素类药物的敏感率很低。革兰阴性杆菌中耐药现象严重, 除碳青霉烯类和少数几种添加酶抑制剂的合成青霉素敏感性较高外, 头孢二、三代抗菌药物和喹诺酮类敏感率低。结论: 我院ICU病房常见致病菌耐药情况较严重, 仍需对常见致病菌的药敏情况和用药方法加以重视。ICU医生应定期关注致病菌的流行情况, 掌握致病菌的分布、药敏状况及抗菌药物的使用情况, 合理使用抗菌药物。
- 抗菌药物 /
- 合理用药 /
- 致病菌流行状况
Abstract: Objective: To observe state of epidemic of the pathogenic bacterial and condition of sensitivity in order to provide theoretical basis for reducing drug resistance and evidence for clinicians to choose antibiotics appropriately in our hospital.Method: Pathogenic bacterial and results of antimicrobial susceptibility test of positive samples in our hospital from January in 2015 to December in 2017 were collected and analyzed.Result: Eight hundred and thirty-four bacterial strains were isolated from January in 2015 to December in 2017, in which the ration of gram-positivebacteriaandgram-negativebacteria was 23.7% and 72.1%, respectively.Among gram-positive bacteria, staphylococcus aureus and staphylococcus epidermidis were only sensitive to vancomycin, linezolid and KuiNuputin/dafoeleptin.They showed low sensitivity to clindamycin, penicillin and erythromycin.A serious drug resistance existed among gram-negative bacterial.The sensitive rate of second-generation, third-generation cephalosporin and quinolones was low, but carbapenems and several synthetic penicillins adding enzyme inhibitor showed a high sensitivity to them.Conclusion: Drug resistance of pathogenic bacterial is severe and we should pay attention to rational drug use.Our doctors should periodically concern the prevalence of pathogenic bacterial in their hospital and master the information about distribution of pathogens, drug sensitivity and usage of antibacterial drugs, thus promote the rational use of antimicrobial agents in clinic.
- antimicrobials /
- rational drug use /
- pathogen prevalence

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