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摘要: 烟雾吸入性急性肺损伤是烧伤患者发病率和死亡率较高的主要原因,其病理生理机制复杂,治疗上仍以支持治疗为主,并且目前国内外尚无统一的烟雾吸入性急性肺损伤的临床治疗指南或共识,目前已有多种针对性药物为临床治疗提供了新的思路和方法。本文就近10年来烟雾吸入性急性肺损伤的病理生理机制及目前针对性药物治疗的进展作一综述。
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关键词:
- 烟雾吸入性急性肺损伤 /
- 病理生理 /
- 治疗
Abstract: Smoke inhalation-induced acute lung injury is the main cause of morbidity and mortality in burn patients. The pathophysiological mechanisms of this injury are complex, and supportive care remains the mainstay of treatment. Currently, there is no unified clinical treatment guideline or consensus for smoke inhalation-induced acute lung injury, both domestically and abroad. However, several targeted drugs have provided new ideas and methods for clinical treatment. This article provides a review of the pathophysiological mechanisms of smoke inhalation-induced acute lung injury over the past 10 years, as well as the current progress in targeted drug therapy.-
Key words:
- smoke inhalation-induced acute lung injury /
- pathophysiology /
- therapies
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