Research progress in treatment of out-of-hospital cardiac arrest after resuscitation
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摘要: 院外心脏骤停(OHCA)带来了巨大的全球死亡率和发病率, 及时的心肺复苏是提高生存率的最重要措施, 而复苏后的治疗影响着幸存者的生活质量与神经功能结果。国内外多个协会颁布了OHCA复苏后治疗的指南, 但在许多问题上还存在争议, 缺乏最佳临床标准。本文就复苏后治疗中的关键问题, 包括靶向温度管理(TTM)、目标血压和氧合以及侵入性管理措施等方面进行探讨, 旨在为临床实践与后续的研究提供参考。Abstract: Out-of-hospital cardiac arrest(OHCA) carries substantial global mortality and morbidity, and timely cardiopulmonary resuscitation is the most important measure to improve survival, whereas treatment after resuscitation affects survivors' quality of life and neurological outcomes. Several associations at home and abroad have issued guidelines for post resuscitation treatment of OHCA, but there are still controversies on many issues and lack of optimal clinical standards. This article explores key issues in post resuscitation therapy, including targeted temperature management(TTM), targeted blood pressure and oxygenation, and invasive management measures, with the aim of informing clinical practice with subsequent research.
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