心脏骤停后综合征相关急性胃肠损伤的研究进展

刘国祥; 朱长清; 王世伟; 贾天元; 罗成准; 王子达; 尚召明; 陆晓晔; 杨倩

doi:10.13201/j.issn.1009-5918.2021.09.014

心脏骤停后综合征相关急性胃肠损伤的研究进展

- 上海交通大学医学院附属仁济医院急诊科(上海,200001)
基金项目:
国家自然科学基金资助项目(No:81971803)

详细信息

通讯作者: 朱长清,E-mail:zhucq1965@126.com

中图分类号: R459.7

收稿日期: 2021-04-21

Research progress in post cardiac arrest syndrome associated with acute gastrointestinal injury

More Information

Corresponding author: ZHU Zhangqing, E-mail: zhucq1965@126.com

Received Date: 21 April 2021

摘要

- 心脏骤停 /
- 心脏骤停后综合征 /
- 急性胃肠损伤 /
- 急性胃肠损伤分级 /
- 生物标记物
Abstract: Post-cardiac arrest syndrome(PCAS), formerly known as "post-resuscitation syndrome", is consisted of acute ischemia-reperfusion injury and a series of complex pathobiological changes, which occur simultaneously in patients with restoration of spontaneous circulation by cardiopulmonary resuscitation(CPR). Studies have shown that gastrointestinal tract is one of the earliest and most serious damaged organs in the pathophysiological process of PCAS. It is another common organ injury second only to heart and brain injury after resuscitation. Moreover, it is also considered as the "power" source for the progression of PCAS to multiple organ dysfunction syndrome. Therefore, how to carry out early prevention, diagnosis and clinical intervention is vital for curbingthe occurrence and development of acute gastrointestinal injury(AGI) afterresuscitation. This article reviews the epidemiological status, pathophysiological mechanism, grading system, evaluation methods and treatment of AGI after CPR, so as to provide some reference for the early diagnosis and treatment of PCAS-related AGI.
- cardiac arrest /
- post-cardiac arrest syndrome /
- acute gastrointestinal injury /
- acute gastrointestinal injury grade /
- biomarker

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