Advance in the anticoagulant therapy for sepsis-associated coagulopathy and disseminated intravascular coagulation
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Abstract: Sepsis-associated coagulopathy is defined as increased international normalized ratio and decreased platelet count. It is a highly predictive indicator of 28 day mortality. With the continuous development of this coagulation disorder, it can lead to coagulation and blood flow damage of microvessels and large vessels, the occurrence of disseminated intravascular coagulation and eventually lead to multiple organ dysfunction. So far, whether anticoagulant therapy is needed remains the focus of debate at home and abroad. Based on this, the article will review the latest treatment progress of SAC and DIC.
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