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摘要: 目的:创伤性脑损伤(TBI)是神经外科常见的损伤,其中低钠血症的发生率约为33%。本研究探讨了低钠血症与TBI不同损伤部位及其他合并因素之间的关系;方法:对我院2017-01—2020-01期间收治的126例TBI患者进行回顾性分析。采用χ2检验分析低钠血症的发生与TBI不同损伤部位、格拉斯哥昏迷评分(GCS)、是否行手术治疗、脑水肿、颅底骨折之间的关系。结果:126例患者中,38例患者(30.16%)出现低钠血症,88例患者(69.84%)血钠正常。TBI患者发生低钠血症与额部损伤(P=0.027)、弥散性轴索损伤(P=0.02)、合并颅底骨折(P=0.025)、合并脑水肿(P=0.044)相关,与颞部损伤、枕部损伤、是否手术、GCS评分无关。结论:研究表明,TBI额部损伤、弥漫性轴索损伤、合并颅底骨折、合并脑水肿患者易发生低钠血症,而颞部损伤、GCS评分、是否手术均不是低钠血症的危险因素。Abstract: Objective: Traumatic brain injury is a common injury in neurosurgery, and the incidence of hyponatremia is about 33%. The incidence of hyponatremia after traumatic brain injury was 33%. Hyponatremia is one of the leading causes of disability and/or death in TBI patients. This study investigated the relationship between hyponatremia and different injury sites and types of TBI. Method: The TBI patients admitted to our hospital were retrospectively analyzed. The χ2 test was used to analyze the relationship between the occurrence of hyponatremia and different injury sites/types of TBI, glasgow coma score(GCS), whether to undergo surgical treatment, and the presence of brain edema/skull base fracture or not. Result: Of the 126 patients, 38(30.16%) developed hyponatremia and 88(69.84%) had normal serum sodium. Hyponatremia in TBI Patients was associated with frontal injury(P=0.027), diffuse axonal injury(P=0.02), combine with skull base fracture(P=0.025), and combined brain edema(P=0.044), but not with temporal injury, occipital injury, surgery, or GCS score.Conclusion: Statistical analysis shows that patients with TBI frontal injury, diffuse axonal injury, combined skull base fracture, and combined brain edema are Prone to hyponatremia, while temporal injury, GCS score, and surgery are not risk factors for hyponatremia.
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Key words:
- traumatic brain injury /
- hyponatremia /
- encephaledema /
- glasgow coma score
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