创伤性脑损伤相关神经特异性血清生物学标记物的研究进展

翁山山; 聂虎

doi:10.13201/j.issn.1009-5918.2020.03.016

创伤性脑损伤相关神经特异性血清生物学标记物的研究进展

翁山山,
聂虎^,

- 四川大学华西医院急诊科(成都, 610041)

详细信息

通讯作者: 聂虎,E-mail:456nh@163.com

中图分类号: R651.15

收稿日期: 2020-02-18

Neuro-specific serum biological markers associated with traumatic brain injury

More Information

Corresponding author: , E-mail: 456nh@163.com

Received Date: 18 February 2020

摘要

- 创伤性脑损伤 /
- 血清生物学标记物 /
- 影像学表现 /
- 预后
Abstract: Traumatic brain injury(TBI) is the leading cause of death and disability in patients with various types of trauma. Assessing the severity and prognosis of TBI can help to rationally use medical resources and guide treatment. The evaluation of traumatic brain injury severity and prognosis depends on clinical manifestations and imaging examinations. At present, there are no good biological tools to accurately diagnose traumatic brain injury or dynamic assessment,which cannot reflect the progress of the disease timely and effectively. In recent years, a large number of studies have investigated serum biomarkers of glial cell or neuron damage, which can be used as indicators for evaluating the severity of brain injury and the poor prognosis of TBI patients. This article will review the current TBI-related serum biomarkers in order to provide a reference for further discussion of a better TBI prognosis evaluation system.
- traumatic brain injury /
- serum biomarkers /
- imaging examinations /
- prognosis

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参考文献(69)

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