Abstract: Objective: To explore the clinical effect of early and Ⅱ stage debridement in treating bleeding tendency of snakebite patients.Method: Seventy-two patients with finger bitten by explicitly snake venom types admitted in our department in March 2016 to October were selected as the research object.The patients were randomly divided into a,b,c,d four groups according to the snake species.The tendency of bleeding and clinical efficacy were analyzed by comparing the swelling of the patients,thrombocytopenia, subcutaneous purpura and wound healing.Result: No difference in the incidence of limb hemorrhage was found in 47 cases of iron head snake bite.There was no significant difference in the incidence of the onset of limb bleeding in 25 cases of viper bite (P<0.05).The rate of hemorrhage in patients with soldering iron head bites was significantly higher (P<0.05).There were 47 cases of welding head snake bites,25 patients bitten by agkistrodon halys.The difference had no difference in the limb condition evolution (wrist joint swelling,elbow joint swelling,10 cm elbow swelling,thrombocytopenia purpura).The incidence of hemorrhage in patients with soldering iron head bites was higher than that of viper (P<0.05).No matter what kind of snake wound,wound swelling in patients of early and Ⅱ stage debridement treatment was less than patients who were not in Ⅱ-stage debridement,but healing time prolongs,and the differences were statistically significant (P<0.05).Conclusion: Snake poison kinds of platelet consumption,blood coagulation dysfunction is direct factors,cannot achieve contain venom spread in ferrite Ⅱ-stage debridement and reduce the damage to the organization but can effectively reduce the snake venom on the body damage.