Abstract: Objective:This study was designed to analyze the risk factors of sudden death(SD) and to identify the high-risk groups in order to explore the prevention and reduction of sudden death.Method:The clinical data of 288 cases of SD patients admitted in emergency department of our hospital nearly three years were retrospectively analyzed.Information including genders,age,the time of death,seasons,basic diseases,inducing factors were retrospectively analyzed.Result:There were significant more male patients than female patients in our study,and the gender ratio was 2.74:1.Male patients aged 40~79 had the highest incidence of SD which accounts of 55.2%.The onset of SD had two peak times and were 7~9AM and 7~9PM respectively.Higher incidence of SD occurred in the first and the forth seasons.Cardiovascular diseases were main cause of SD and were accounted for 76.4%.119 cases of SD had explicit inducing factors,including over fatigue,emotion,drinking and smoking.Cardiovascular and cerebrovascular diseases accounted for 68.8% of SD causes.Conclusion:Male over the age of 40 with cardiovascular and cerebrovascular diseases were high-risk group of SD.This group of people should be strengthened to prevent the SD in the end winter and early spring,including quit smoking and drinking,keep a good mood,avoid over fatigue,physical exercise appropriately,health education and periodic physical examination.