成人心肺复苏中非同步机械通气的管理策略

郭辉, 钟燕, 李昌盛, 等. 成人心肺复苏中非同步机械通气的管理策略[J]. 临床急诊杂志, 2022, 23(11): 800-806. doi: 10.13201/j.issn.1009-5918.2022.11.011
引用本文: 郭辉, 钟燕, 李昌盛, 等. 成人心肺复苏中非同步机械通气的管理策略[J]. 临床急诊杂志, 2022, 23(11): 800-806. doi: 10.13201/j.issn.1009-5918.2022.11.011
GUO Hui, ZHONG Yan, LI Changsheng, et al. Management strategy of asynchronous mechanical ventilation in adults during cardiopulmonary resuscitation[J]. J Clin Emerg, 2022, 23(11): 800-806. doi: 10.13201/j.issn.1009-5918.2022.11.011
Citation: GUO Hui, ZHONG Yan, LI Changsheng, et al. Management strategy of asynchronous mechanical ventilation in adults during cardiopulmonary resuscitation[J]. J Clin Emerg, 2022, 23(11): 800-806. doi: 10.13201/j.issn.1009-5918.2022.11.011

成人心肺复苏中非同步机械通气的管理策略

  • 基金项目:
    湖北省十堰市科技局指导项目(No:19Y36)
详细信息
    通讯作者: 钟燕,E-mail:461657288@qq.com

    Δ审校者

  • 中图分类号: R541.78

Management strategy of asynchronous mechanical ventilation in adults during cardiopulmonary resuscitation

More Information
  • 心肺复苏国际指南建议对心搏骤停患者进行有效的通气,心搏骤停后呼吸系统顺应性下降,胸外按压中呼吸系统又有其特殊的呼吸力学变化,故机械通气不同于传统常规设置方法,然而目前最佳机械通气策略尚未建立,临床医生面临呼吸机管理策略问题,本综述的目的是总结目前不同的研究,提出非同步机械通气的初步管理策略:推荐PRVC通气模式、100%的吸氧浓度、通气频率10次/min、潮气量500~600 mL、关闭触发功能、峰压报警上限设置为80 cmH2O(1 cmH2O=0.098 kPa)及5 cmH2O PEEP。心搏骤停患者心肺复苏中非同步通气的最佳的策略仍需要进一步研究。
  • 加载中
  • [1]

    Tang Y, Sun M, Zhu A. Outcome of cardiopulmonary resuscitation with different ventilation modes in adults: A meta-analysis[J]. Am J Emerg Med, 2022, 57: 60-69.

    [2]

    文才, 余涛, 王立祥. 心肺复苏过程中机械通气策略研究进展[J]. 中华危重病急救医学, 2017, 29(9): 853-856. doi: 10.3760/cma.j.issn.2095-4352.2017.09.018

    [3]

    Cordioli RL, Brochard L, Suppan L, et al. How Ventilation Is Delivered During Cardiopulmonary Resuscitation: An International Survey[J]. Respir Care, 2018, 63(10): 1293-1301. doi: 10.4187/respcare.05964

    [4]

    Liu YC, Qi YM, Zhang H, et al. A survey of ventilation strategies during cardiopulmonary resuscitation[J]. World J Emerg Med, 2019, 10(4): 222-227. doi: 10.5847/wjem.j.1920-8642.2019.04.005

    [5]

    付阳阳, 刘丹瑜, 金魁, 等. 关于机械通气对心肺复苏患者通气效果的回顾性研究[J]. 临床急诊杂志, 2019, 20(5): 343-347. doi: 10.13201/j.issn.1009-5918.2019.05.002

    [6]

    Sanson G, Ristagno G, Caggegi GD, et al. Impact of 'synchronous' and 'asynchronous' CPR modality on quality bundles and outcome in out-of-hospital cardiac arrest patients[J]. Intern Emerg Med, 2019, 14(7): 1129-1137. doi: 10.1007/s11739-019-02138-9

    [7]

    Aggelina A, Pantazopoulos I, Giokas G, et al. Continuous chest compressions with asynchronous ventilation improve survival in a neonatal swine model of asphyxial cardiac arrest[J]. Am J Emerg Med, 2021, 48: 60-66. doi: 10.1016/j.ajem.2021.04.009

    [8]

    Vali P, Lesneski A, Hardie M, et al. Continuous chest compressions with asynchronous ventilations increase carotid blood flow in the perinatal asphyxiated lamb model[J]. Pediatr Res, 2021, 90(4): 752-758. doi: 10.1038/s41390-020-01306-4

    [9]

    Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care[J]. Circulation, 2020, 142(16_suppl_2): S366-S468.

    [10]

    Neumamm LBA, Jardim-Neto AC, Motta-Ribeiro GC. Empirical evidence for safety of mechanical ventilation during simulated cardiopulmonary resuscitation on a physical model[J]. Am J Emerg Med, 2021, 48: 312-315. doi: 10.1016/j.ajem.2021.06.062

    [11]

    庄载受, 梁艳, 薛盛东, 等. 压力调节容量控制通气模式在心肺复苏中的临床疗效观察[J]. 中华重症医学电子杂志, 2017, 3(1): 55-59. doi: 10.3877/j.issn.2096-1537.2017.01.012

    [12]

    李彬, 李名燚, 谢雯, 等. 早期建立PRVC模式通气配合胸外按压对心脏骤停患者心肺复苏后颅脑功能及氧代谢水平的影响[J]. 新疆医科大学学报, 2018, 41(12): 1476-1479, 1484. doi: 10.3969/j.issn.1009-5551.2018.12.006

    [13]

    Ruemmler R, Ziebart A, Kuropka F, et al. Bi-Level ventilation decreases pulmonary shunt and modulates neuroinflammation in a cardiopulmonary resuscitation model[J]. PeerJ, 2020, 8: e9072. doi: 10.7717/peerj.9072

    [14]

    Fuest K, Dorfhuber F, Lorenz M, et al. Comparison of volume-controlled, pressure-controlled, and chest compression-induced ventilation during cardiopulmonary resuscitation with an automated mechanical chest compression device: A randomized clinical pilot study[J]. Resuscitation, 2021, 166: 85-92. doi: 10.1016/j.resuscitation.2021.07.010

    [15]

    Singh G, Chien C, Patel S. Pressure Regulated Volume Control(PRVC): Set it and forget it[J]? Respir Med Case Rep, 2019, 29: 100822.

    [16]

    Dincel E. Advanced mechanical ventilation modes: design and computer simulations[J]. Comput MethodsBiomech Biomed Engin, 2021, 24(6): 673-686. doi: 10.1080/10255842.2020.1845319

    [17]

    张锋, 张小冬. 院内心搏骤停患者机械通气时机的选择及与预后的关系[J]. 中华危重病急救医学, 2016, 28(12): 1104-1107. doi: 10.3760/cma.j.issn.2095-4352.2016.12.008

    [18]

    Spindelboeck W, Schindler O, Moser A, et al. Increasing arterial oxygen partial pressure during cardiopulmonary resuscitation is associated with improved rates of hospital admission[J]. Resuscitation, 2013, 84(6): 770-775. doi: 10.1016/j.resuscitation.2013.01.012

    [19]

    Patel JK, Kataya A, Parikh PB. Association between intra-and post-arrest hyperoxia on mortality in adults with cardiac arrest: A systematic review and meta-analysis[J]. Resuscitation, 2018, 127: 83-88. doi: 10.1016/j.resuscitation.2018.04.008

    [20]

    Patel JK, Schoenfeld E, Parikh PB, et al. Association of Arterial Oxygen Tension During In-Hospital Cardiac Arrest With Return of Spontaneous Circulation and Survival[J]. J Intensive Care Med, 2018, 33(7): 407-414. doi: 10.1177/0885066616658420

    [21]

    LA Via L, Astuto M, Bignami EG, et al. The effects of exposure to severe hyperoxemia on neurological outcome and mortality after cardiac arrest[published online ahead of print, 2022 Mar 23][J]. Minerva Anestesiol, 2022.

    [22]

    Wyckoff MH, Singletary EM, Soar J, et al. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group[J]. Resuscitation, 2021, 169: 229-311. doi: 10.1016/j.resuscitation.2021.10.040

    [23]

    Orso D, Vetrugno L, Federici N, et al. Mechanical Ventilation Management During Mechanical Chest Compressions[J]. Respir Care, 2021, 66(2): 334-346. doi: 10.4187/respcare.07775

    [24]

    Halter M, Jouffroy R, Saade A, et al. Association between hyperoxemia and mortality in patients treated by eCPR after out-of-hospital cardiac arrest[J]. Am J Emerg Med, 2020, 38(5): 900-905. doi: 10.1016/j.ajem.2019.07.008

    [25]

    Roberts BW, Kilgannon JH, Hunter BR, et al. Association Between Early Hyperoxia Exposure After Resuscitation From Cardiac Arrest and Neurological Disability: Prospective Multicenter Protocol-Directed CohortStudy[J]. Circulation. 2018;137(20): 2114-2124. doi: 10.1161/CIRCULATIONAHA.117.032054

    [26]

    McGuigan PJ, Shankar-Hari M, Harrison DA, et al. The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study[J]. Crit Care, 2020, 24(1): 336. doi: 10.1186/s13054-020-03039-6

    [27]

    Johnson NJ, Carlbom DJ, Gaieski DF. Ventilator Management and Respiratory Care After Cardiac Arrest: Oxygenation, Ventilation, Infection, and Injury[J]. Chest, 2018, 153(6): 1466-1477. doi: 10.1016/j.chest.2017.11.012

    [28]

    Mohamed BA. Airway Management During Cardiopulmonary Resuscitation[published online ahead of print, 2022 Mar 25][J]. Curr Anesthesiol Rep, 2022: 1-10.

    [29]

    Newell C, Grier S, Soar J. Airway and ventilation management during cardiopulmonary resuscitation and after successful resuscitation[J]. Crit Care, 2018, 22(1): 190. doi: 10.1186/s13054-018-2121-y

    [30]

    Wang HE, Jaureguibeitia X, Aramendi E, et al. Airway strategy and ventilation rates in the pragmatic airway resuscitation trial[J]. Resuscitation, 2022, 176: 80-87. doi: 10.1016/j.resuscitation.2022.05.008

    [31]

    Vissers G, Soar J, Monsieurs KG. Ventilation rate in adults with a tracheal tube during cardiopulmonary resuscitation: A systematic review[J]. Resuscitation, 2017, 119: 5-12. doi: 10.1016/j.resuscitation.2017.07.018

    [32]

    Carlson JN, Wang HE. Optimal Airway Management in Cardiac Arrest[J]. Crit Care Clin, 2020, 36(4): 705-714. doi: 10.1016/j.ccc.2020.07.008

    [33]

    Vanwulpen M, Wolfskeil M, Duchatelet C, et al. Do manual chest compressions provide substantial ventilation during prehospital cardiopulmonary resuscitation[J]? Am J Emerg Med, 2021, 39: 129-131. doi: 10.1016/j.ajem.2020.09.037

    [34]

    McDannold R, Bobrow BJ, Chikani V, et al. Quantification of ventilation volumes produced by compressions during emergency department cardiopulmonary resuscitation[J]. Am J Emerg Med, 2018, 36(9): 1640-1644. doi: 10.1016/j.ajem.2018.06.057

    [35]

    Duchatelet C, Kalmar AF, Monsieurs KG, et al. Chest compressions during ventilation in out-of-hospital cardiac arrest cause reversed airflow[J]. Resuscitation, 2018, 129: 97-102. doi: 10.1016/j.resuscitation.2018.03.035

    [36]

    Van Den Daele C, Vanwulpen M, Hachimi-Idrissi S. Chest compressions during ventilation in out-of-hospital cardiopulmonary resuscitation cause fragmentation of the airflow[J]. Am J Emerg Med, 2021, 50: 455-458. doi: 10.1016/j.ajem.2021.08.028

    [37]

    Orlob S, Wittig J, Hobisch C, et al. Reliability of mechanical ventilation during continuous chest compressions: a crossover study of transport ventilators in a human cadaver model of CPR[J]. Scand J Trauma Resusc Emerg Med, 2021, 29(1): 102.

    [38]

    Magliocca A, Rezoagli E, Zani D, et al. Cardiopulmonary Resuscitation-associated Lung Edema(CRALE). A Translational Study[J]. Am J Respir Crit Care Med. 2021;203(4): 447-457.

    [39]

    Beloncle FM, Merdji H, Lesimple A, et al. Gas Exchange and Respiratory Mechanics after a Cardiac Arrest: A Clinical Description of Cardiopulmonary Resuscitation-associated Lung Edema[J]. Am J Respir Crit Care Med, 2022, 206(5): 637-640.

    [40]

    Olasveengen TM, de Caen AR, Mancini ME, et al. 2017 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Summary[J]. Resuscitation, 2017, 121: 201-214.

    [41]

    Ching CK, Leong BS, Nair P, et al. Singapore Advanced Cardiac Life Support Guidelines 2021[J]. Singapore Med J, 2021, 62(8): 390-403.

    [42]

    Cordioli RL, Lyazidi A, Rey N, et al. Impact of ventilation strategies during chest compression. An experimental study with clinical observations[J]. J Appl Physiol(1985), 2016, 120(2): 196-203.

    [43]

    Beitler JR, Ghafouri TB, Jinadasa SP, et al. Favorable Neurocognitive Outcome with Low Tidal Volume Ventilation after Cardiac Arrest[J]. Am J Respir Crit Care Med, 2017, 195(9): 1198-1206.

    [44]

    Sutherasan Y, Vargas M, Brunetti I, et al. Ventilatory targets after cardiac arrest[J]. Minerva Anestesiol, 2015, 81(1): 39-51.

    [45]

    Tan D, Xu J, Shao S, et al. Comparison of different inspiratory triggering settings in automated ventilators during cardiopulmonary resuscitation in a porcine model[J]. PLoS One, 2017, 12(2): e0171869.

    [46]

    Sahu AK, Timilsina G, Mathew R, et al. "Six-dial Strategy"-Mechanical Ventilation during Cardiopulmonary Resuscitation[J]. Indian J Crit Care Med, 2020, 24(6): 487-489.

    [47]

    Chalkias A, Pavlopoulos F, Koutsovasilis A, et al. Airway pressure and outcome of out-of-hospital cardiac arrest: A prospective observational study[J]. Resuscitation, 2017, 110: 101-106.

    [48]

    王伟钟, 姚晓燕, 徐唯超, 等. 心肺复苏时呼吸机高压报警上限与吸气触发灵敏度合理设置的临床研究[J]. 中国现代医学杂志, 2021, 31(3): 80-83. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXDY202103016.htm

    [49]

    Kim JW, Lee JW, Ryu S, et al. Changes in peak inspiratory flow rate and peak airway pressure with endotracheal tube size during chest compression[J]. World J Emerg Med, 2020, 11(2): 97-101.

    [50]

    Cordioli RL, Grieco DL, Charbonney E, et al. New physiological insights in ventilation during cardiopulmonary resuscitation[J]. Curr Opin Crit Care. 2019;25(1): 37-44.

    [51]

    Neth MR, Idris A, McMullan J, et al. A review of ventilation in adult out-of-hospital cardiac arrest[J]. J Am Coll Emerg Physicians Open, 2020, 1(3): 190-201.

    [52]

    Duchatelet C, Wolfskeil M, Vanwulpen M, et al. Effect of positive end-expiratory pressure during cardiopulmonary resuscitation on short-term survival[J]. Resuscitation 2019;142: e7-e8.

    [53]

    Levenbrown Y, Hossain MJ, Keith JP, et al. The effect of positive end-expiratory pressure on cardiac output and oxygen delivery during cardiopulmonary resuscitation[J]. Intensive Care Med Exp, 2020, 8(1): 36.

  • 加载中
计量
  • 文章访问数:  1484
  • PDF下载数:  507
  • 施引文献:  0
出版历程
收稿日期:  2022-08-02
刊出日期:  2022-11-10

目录