Prognostic value of simple thrombo-inflammation score in patients with acute ST-segment elevation myocardial infarction
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摘要: 目的:探究简易血栓炎症预后评分(sTIPS)对ST段抬高型心肌梗死(STEMI)患者预后的预测价值。方法:回顾性分析2018年1月1日—2019年6月30日期间就诊于西南医科大学附属中医医院426例STEMI患者的人口学资料、生命体征、实验室检查等资料,并随访纳入患者1年的生存情况。根据sTIPS评分标准分为0分组、1分组和2分组,采用多因素Cox回归分析影响STEMI患者死亡的独立危险因素。结果:sTIPS分值0分、1分和2分SETMI患者住院死亡率分别为2.54%、5.83%、17.02%(P<0.001),随访期间死亡率分别为7.97%、22.33%、57.45%(P<0.001)。随着sTIPS分值增高,STEMI患者GRACE评分和Genisini评分逐渐增高,差异均有统计学意义(P<0.001)。多因素Cox回归分析显示,高sTIPS评分是STEMI患者死亡的独立危险因素(1 vs.0,HR=2.127,95%CI:1.253~4.967,P=0.037;2 vs.0,HR=6.582,95%CI:3.289~9.225,P<0.001)。结论:sTIPS评分可用于STEMI患者危险评估,有助于早期危险分层指导临床精准干预。
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关键词:
- 简易血栓炎症预后评分 /
- ST段抬高型心肌梗死 /
- 死亡
Abstract: Objective: To explore the prognostic value of simple Thrombo-Inflammatory Prognostic Score(sTIPS) in patients with ST-segment elevation myocardial infarction(STEMI).Methods: The demographic data, vital signs, laboratory examination and other data of 426 patients with STEMI admitted to the Affiliated Hospital of Southwest Medical University and the Affiliated Hospital of Traditional Chinese Medicine from January 1, 2018 to June 30, 2019 were retrospectively analyzed, and the 1-year survival situation of the included patients was followed up. According to the sTIPS score, the patients were divided into 0, 1 and 2. Multivariate Cox regression analysis was used to analyze the independent risk factors of death in STEMI patients.Results: The in-hospital mortality of patients with sTIPS score 0, 1 and 2 was 2.54% vs. 5.83% vs. 17.02%(P<0.001), and the mortality during follow-up was 7.97% vs. 22.33% vs. 57.45%(P<0.001). With the increase of sTIPS score, GRACE score and Genisini score of STEMI patients increased gradually, and the differences were statistically significant(P<0.001). Multivariate Cox regression analysis showed that high sTIPS score was an independent risk factor for death in STEMI patients(1 vs. 0, HR=2.127, 95%CI: 1.253-4.967, P=0.037; 2 vs. 0, HR=6.582, 95%CI: 3.289-9.225, P<0.001).Conclusion: sTIPS score can be used for risk assessment of STEMI patients, which is helpful for early risk stratification and guiding clinical precise intervention. -
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