Effects of early and late interventional therapy on long-term prognosis in high-risk patients with non-ST-segment elevation acute myocardial infarction
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摘要: 目的:分析非ST段抬高型心肌梗死(NSTEMI)高危患者早期及晚期介入两种不同处理方式对患者远期预后的影响。方法:回顾性分析2017年1月—2019年12月广西壮族自治区人民医院胸痛中心收治的186例GRACE评分>140患者的临床资料,根据患者行PCI治疗时间分为早期治疗组(≤48 h)及晚期治疗组(>48 h),比较两种不同的处理方式对于NSTEMI高危患者远期预后的影响。结果:在NSTEMI高危患者中,早期介入治疗组在复合终点(心源性及非心源性死亡、再发心肌梗死、再次血运重建、心绞痛住院)及次要终点事件(心绞痛复发、出血、心律失常、心力衰竭住院、卒中)的发生率均低于晚期治疗组,两组间差异具有统计学意义(均P<0.05)。结论:早期介入治疗对NSTEMI高危患者可能是一个较为理想的治疗策略,临床医师需要从患者可能获益和潜在风险两方面做出整体评估,才可能为患者提供最理想的选择。
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关键词:
- 非ST段抬高型心肌梗死 /
- 介入 /
- 早期 /
- 预后
Abstract: Objective: To analyze the effects of early and late intervention on the long-term prognosis of high-risk patients with non-ST-segment elevation acute myocardial infarction(NSTEMI).Methods: A retrospective analysis was performed on 186 patients admitted to the chest pain centre of guangxi zhuang autonomous region people's hospital, with GRACE> 140 from January 2017 to December 2019, According to the time of PCI treatment, patients were divided into early treatment group(≤48 h) and late treatment group(>48 h), Comparing the effects of two different treatments on the long-term prognosis of high-risk patients with NSTEMI.Results: The effects of early and late intervention on the long-term prognosis of high-risk patients with NSTEMI were retrospectively analyzed. In high risk patients with NSTEMI, the incidence of composite endpoints(cardiac and non cardiac death and myocardial infarction, again reascularization, angina pectoris in hospital) and secondary endpoints(angina recurrence, bleeding, arrhythmia, heart failure hospitalization, stroke) in the early interventional treatment group was lower than that in the late treatment group, there is a statistically significant difference between the two groups(all P<0.05).Conclusion: Early intervention may be an ideal treatment strategy for patients at high risk of NSTEMI, and clinicians need to make an overall assessment from both the possible benefits and the potential risks to provide the most ideal choice for patients.-
Key words:
- non-ST-segment elevation myocardial infarction /
- intervention /
- early /
- prognosis
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