百草枯中毒临床治疗的回顾性分析

陈功雷; 谢芬; 郁毅刚; 陈桂喜

doi:10.13201/j.issn.1009-5918.2018.09.011

百草枯中毒临床治疗的回顾性分析

- 解放军第175医院厦门大学附属东南医院急诊科(福建漳州, 363000)

详细信息

通讯作者: 陈桂喜,E-mail:342258949@qq.com

中图分类号: R595.4

收稿日期: 2018-08-03

Retrospective analysis of clinical treatment of paraquat poisoning

- Department of Emergency, PLA No. 175 Hospital, Southeast Affiliated Hospital of Xiamen University, Fujian, Zhangzhou, 363000, China

More Information

Corresponding author: CHEN Guixi, E-mail: 342258949@qq.com

Received Date: 03 August 2018

摘要

摘要: 目的:研究百草枯中毒患者的主要特征及临床治疗的有效方法。方法:回顾性分析本院近3年收治的91例百草枯中毒患者的临床资料,比较存活组和死亡组两组不同患者的一般情况、中毒剂量、检查结果及治疗方法等指标。将有统计学差异的指标(P<0.05)进行条件Logistic回归分析,找出影响患者预后的独立危险因素,并通过ROC曲线评价其对患者预后的影响。结果:中毒剂量、肌酐、尿素氮、丙氨酸转氨酶是百草枯中毒患者死亡的独立危险因素(P<0.05),血液灌流治疗可提高患者的存活率。结论:中毒剂量、肌酐、尿素氮、丙氨酸转氨酶可作为判断百草枯中毒患者病情严重程度及预后的可靠指标,血液灌流是治疗百草枯中毒患者的有效方法。
- 百草枯中毒 /
- 临床治疗 /
- 回顾性分析
Abstract: Objective:To study the main characteristics and effective clinical treatment of paraquat poisoning patients. Method:The clinical data of 91 cases of paraquat poisoning patients treated in the hospital for the past three years were retrospectively analyzed.The general conditions,toxic dose,examination results and treatment methods of the two groups of survivors and death groups were compared.Statistically significant indicators(P<0.05)were subjected to Logistic regression analysis to identify independent risk factors that affected the prognosis of the patients,and their effect on the patient's prognosis was evaluated by ROC curve. Result:Poisoning dose,creatinine,urea nitrogen,alanine aminotransferase were independent risk factors for death in patients with paraquat poisoning(P<0.05),and hemoperfusion treatment could improve the survival rate of patients.Conclusion:Poisoning dose,creatinine,urea nitrogen,alanine aminotransferase can be used as a reliable index to judge the severity and prognosis of paraquat poisoning patients.Hemoperfusion is an effective method for the treatment of paraquat poisoning patients.
- paraquat poisoning /
- clinical treatment /
- retrospective analysis

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参考文献(8)

[1]	Sun B, He Y.Paraquat poisoning mechanism and its clinical treatment progress[J].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue, 2017, 29 (11):1043-1046.
[2]	Banday TH, Bashir Bhat S, Bashir Bhat S.Manifestation, complications and clinical outcome in paraquat poison?A hospital based study in a rural area of Karnataka[J].J Environ Occup Sci, 2014, 3 (1):21-24.
[3]	Delirrad M, Majidi M, Boushehri B.Clinical features and prognosis of paraquat poisoning:a review of 41cases[J].Int J Clin Exp Med, 2015, 8 (12):8122-8128.
[4]	Pavan M.Acute kidney injury following Paraquat poisoning in India[J].Iran J Kidney Dis, 2013, 7 (1):64-66.
[5]	Cherukuri H, Pramoda K, Rohini D, et al.Demographics, clinical characteristics and management of herbicide poisoning in tertiary care hospital[J].Toxicol Int, 2014, 21 (2):209-213.
[6]	Marashi SM, Raji H, Nasri-Nasrabadi Z, et al.One lung circumvention, an interventional strategy for pulmonary salvage in acute paraquat poisoning:an evidence based review[J].Tzu Chi Med J, 2015, 27 (1):99-101.
[7]	Dondorp W, De Wert G, Bombard Y, et al.Non-invasive prenatal testing for aneuploidy and beyond:challenges of responsible innovation in prenatal screening[J].Nature Publishing Group, 2015, 23 (11):1438-1450.
[8]	Kavousi-Gharbi S, Jalli R, Rasekhi-Kazerouni A, et al.Discernment scheme for paraquat poisoning:A fiveyear experience in Shiraz, Iran[J].World J Exp Med, 2017, 7 (1):31-39.