严重创伤后免疫细胞功能变化的标志物

蔡芳芳; 陈怿

doi:10.13201/j.issn.1009-5918.2018.02.016

严重创伤后免疫细胞功能变化的标志物

蔡芳芳^1,2,
陈怿^1, ,

- 1. 暨南大学医学院附属东莞医院ICU(广东东莞,523900);
- 2. 暨南大学
基金项目:
东莞市科技局医疗卫生科技计划一般项目 (No:2015105101088)

详细信息

通讯作者: 陈怿, E-mail:chenyi_icu@163.com

中图分类号: R641

收稿日期: 2018-01-18

Markers of immune cell dysfunction induced by major trauma

More Information

Corresponding author: , E-mail: chenyi_icu@163.com

Received Date: 18 January 2018

摘要

- 严重创伤 /
- 免疫功能 /
- 表面受体 /
- 细胞因子 /
- 单核-巨噬细胞
Abstract: Trauma is defined as the damage of organs and tissues caused by external force in daily life.Due to the different of type and location of injury, there are various pathophysiological changes induced by trauma, which result high mortality and disability.Immune dysfunction which is manifested as excessive inflammatory reaction or immunesuppression is caused by major trauma frequently.Uncontrolled immune dysfunction leads to severe organ dysfunction and sacrifice eventually.Base on surface receptors and functional productions, this review summarizes the recent achievements about the markers of immune cells changes caused by trauma, and aims to improve the evaluation, diagnosis and treatment of immune dysfunction induced by trauma.
- major trauma /
- immunologic function /
- surface receptors /
- cytokine /
- lymphocyte

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