急性冠状动脉综合征患者血清Ⅰ CTP、Ⅲ CTP水平与TIMI危险评分的相关性分析

艾文婷; 傅莹莹; 李瑞; 武敏

doi:10.13201/j.issn.1009-5918.2017.06.008

急性冠状动脉综合征患者血清Ⅰ CTP、Ⅲ CTP水平与TIMI危险评分的相关性分析

- 1. 陕西省人民医院心内科(西安, 710068);
- 2. 陕西省人民医院急诊科;
- 3. 安康市汉滨区第一医院心内科;
- 4. 陕西省人民医院内分泌科

详细信息

通讯作者: 武敏, E-mail:wumin175@126.com

中图分类号: R541.4

收稿日期: 2017-04-19

Correlation analysis between serum carboxyl terminal peptide of Ⅰ/Ⅲ type collagen and TIMI risk scores in patients with acute coronary syndrome

- 1 Department of Cardiology, Shaanxi Provincial People's Hospital, Xi'an 710068, China;
- 2 Department of Emergency, Shaanxi Provincial People's Hospital;
- 3 Department of Cardiology, the First Hospital of Hanbin District;
- 4 Department of Endocrinology, Shaanxi Provincial People's Hospital

More Information

Corresponding author: WU Min, E-mail: wumin175@126.com

Received Date: 19 April 2017

摘要

摘要: 目的: 分析急性冠状动脉综合征(ACS)患者血清Ⅰ型、Ⅲ型胶原羧基末端肽(ⅠCTP、ⅢCTP)水平与TIMI危险评分的相关性。方法: 选择2015-01-2016-12在我科治疗的116例ACS患者,分为ST段抬高型心肌梗死组(STEMI组,31例)、非ST段抬高型心肌梗死组(NSTEMI组,20例)和不稳定型心绞痛组(UAP组,65例),选取63例稳定型心绞痛(SAP)患者作为SAP组,另外选择60例已行冠状动脉造影检查的非冠心病患者设置对照组。采用酶联免疫吸附试验法(ELISA)检测各组血清ⅠCTP、ⅢCTP水平。结果: STEMI组、NSTEMI组和UAP组患者的血清ⅠCTP和ⅢCTP水平均显著高于SAP组和对照组(均P<0.05)。STEMI组、NSTEMI组和UAP组患者的血清ⅠCTP和ⅢCTP水平与TIMI危险评分均呈正相关(均P<0.05)。结论: 血清ⅠCTP、ⅢCTP水平可能成为ACS患者危险评估的指标。
- Ⅰ型胶原羧基末端肽 /
- Ⅲ型胶原羧基末端肽 /
- 急性冠状动脉综合征 /
- TIMI危险评分
Abstract: Objective: To analysis the correlation between serum carboxyl terminal peptide of Ⅰ/Ⅲ type collagen (ⅠCTP,ⅢCTP) and TIMI risk score in patients with acute coronary syndrome (ACS).Method: 116 patients with ACS from January 2015 to December 2016 were chosen to participate in the study.They were divided into STEMI group (31 cases),NSTEMI group (20 cases) and UAP group (65 cases).63 stable angina pectoris (SAP) patients in our hospital in the same time were selected as SAP group.And 60 patients without coronary atherosclerotic heart disease who underwent examination of coronary angiography were chosen as control group.Serum ⅠCTP and ⅢCTP were measured by using enzyme-linked immunosorbent assay (ELISA).Result: The level of serumⅠCTP and ⅢCTP in STEMI group,NSTEMI group and UAP group were significantly higher than those in SAP group and control group.In STEMI group,NSTEMI group and UAP group,the levels of serum ⅠCTP and ⅢCTP were positively correlated with TIMI risk scores.Conclusion: For patients with ACS,the levels of serum ⅠCTP and ⅢCTP would be used as an index for evaluating the risk.
- ⅠCTP /
- ⅢCTP /
- acute coronary syndrome /
- TIMI risk scores

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