不同透析方式感染相关性住院风险的队列研究

唐俊; 左满花; 黄德斌

doi:10.13201/j.issn.1009-5918.2016.11.017

不同透析方式感染相关性住院风险的队列研究

- 1. 恩施土家族苗族自治州中心医院肾内科(湖北恩施, 445000);
- 2. 湖北民族学院医学院

详细信息

通讯作者: 左满花,E-mail:39942922@qq.com

中图分类号: R459.5

收稿日期: 2016-09-26

A cohort study of the risk on infection-related hospitalization with different modalities of dialysis

- 1. Department of Nephrology, the Central Hospital of Enshi Tujiazu Miaozu Autonomous Prefecture, Enshi 445000, China;
- 2. HuBei Minzu University Medical College

More Information

Corresponding author: ZUO Manhua, E-mail: 39942922@qq.com

Received Date: 26 September 2016

摘要

摘要: 目的:探讨不同透析方式血液透析、腹膜透析患者感染相关住院风险的差异及其原因。方法:选取2009-01-2015-12我院透析期间生活习惯相同或相似的患者共500例,分为2组,其中腹膜透析250例、血液透析250例,采用回顾性病例调查手段,配对队列研究的方法。对2组患者住院率和住院天数、住院原因进行统计比较。结果:腹部感染及透析相关性感染是2组患者感染相关性住院的主要原因(PD:0.019/0.100,HD:0.017/0.041)。腹膜透析患者感染导致的年住院率约是血液透析患者2倍(0.15,0.09),腹膜透析患者感染相关性住院的风险是血液透析患者感染相关性住院风险的1.55倍,其中透析相关性感染、败血症感染、腹部感染及肌肉骨骼系统感染导致的住院风险,腹膜透析患者是血液透析患者的3.47倍、1.42倍、1.31倍及1.19倍。结论:腹膜透析更易导致患者感染相关性住院,增加了住院率。
- 透析 /
- 相关感染 /
- 影响因素 /
- 住院
Abstract: Objective:Peritonitis is a common complication of peritoneal dialysis (PD),there is no report that the risk of infection-related hospitalization for patients undergoing PD is higher than hemodialysis (HD) patients.Method:A retrospective propensity matched-cohort of patients undergoing continuous dialysis between January 2004 and December 2007 were assembled,In all were 500 cases,among that peritoneal dialysis included 250 cases and hemodialysis included 250 cases.Result:The differences among the demographic characteristic,comorbid conditions,laboratory biochemical indicators between patients of PD and HD were no insignificance.The rate per person-year of infection-related hospitalization that the major reasons were abdominal and dialysis-related infection (PD:0.019/0.100,HD:0.017/0.041) for PD patients was nearly twice higher than HD patients (0.15,0.09).The hazard ratio of infection-related hospitalization for PD patients was 1.55 higher than HD patients,among that hazard ratio of infection-related hospitalization of dialysis-related,septicemia,abdominal and musculoskeletal for PD patients was independently 3.47 higher,1.42 higher,1.31 higher,1.19 higher than HD patients.Conclusion:PD is easier to lead to infecting-related hospitalization and highen the rate of hospitalization and the lethal,so the HD is the optimal choice for the end-stage renal diseases' patients.
- dialysis /
- related-infection /
- influencing-factors /
- hospitalization

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