The efficacy comparison of complete mesocolic excision and traditional colon cancer resection
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摘要: 目的：探讨完整结肠系膜切除术（CME）治疗结肠癌的疗效。方法：回顾性分析2010-03-2011-09在我院接受手术治疗的124例Ⅰ~Ⅲ期结肠癌患者的临床资料，将传统结肠癌根治术患者52例设为传统组，CME患者72例设为CME组，分析并比较2组患者术中及术后的各项指标。结果：CME组和传统组患者清扫淋巴结数目分别为（25.2±2.1）枚和（16.7+1.8）枚，2组比较差异有统计学意义（P<0.05）。2组术中出血量分别为（132.6±15.7） ml和（141.8±13.5） ml，差异无统计学意义。术后3 d内腹腔引流量CME组明显多于传统组，差异有统计学意义（P<0.05），2组术后进食时间、排气时间、引流管拔除时间等术后恢复指标以及住院费用、住院时间等社会经济效应指标比较差异无统计学意义。CME组、传统组术后并发症发生率分别为16.7%、15.4%，差异无统计学意义。2组患者2年总生存率的差异无统计学意义；CME组2年无病生存率明显高于传统组，差异有统计学意义（P<0.05）。结论：与传统结肠癌根治术相比，CME对淋巴结清扫更彻底，能有效改善患者的术后生活质量，且不增加术后并发症发生率及影响术后恢复。Abstract: Objective: To investigate the efficacy of complete mesocolic excision (CME).Method: Clinical data of 124 cases of colon cancer(Ⅰ~Ⅲphase)with radical resection Including CME surgery group of 72 cases and traditional surgery group of 52 cases from March 2010 to September 2011 in our Hospital were retrospective analyzed.Result: The number of removed lymph node in CME and tradftional resection group was (25.2±2.1) and (16.7+1.8) respectively (P<0.05).Operative blood loss was (132.6±15.7) ml and (141.8±13.5) ml in CME and traditional resection group without significant difference.Except for more abdominal drainage volume of 3 days post-operation in CME group(P<0.05),the postoperative recovery indicators of postoperative drainage tube removed time,exhaust time,eating time,and the socioeconomic effects indicators of postoperative hospitalization,hospitalization costs were not significantly different between two groups.CME group and traditional resection grouprespectively.The postoperative complication rate of CME group and traditional group was not significantly different (19.4% VS.16.1%).Conclusion: Compared with traditional radical surgery,CME sweeps lymph nodes more thoroughly,can effectively improve the quality of life of patients after surgery,and does not affect postoperative recovery and increase the risk of postoperative complications.
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