重组人骨形态发生蛋白-2结合纳米晶胶原基骨材料在跟骨骨折治疗中的应用

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收稿日期: 2012-03-28

Application of recombinant human bone morphogenetic protein-2 mixed with nano-hydroxyapatite collagen for calcaneal fractures

- Department of Orthopedics, Xiangyang Central Hospital, Xiangyang, Hubei, 441021, China

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Received Date: 28 March 2012

摘要: 目的：应用重组人骨形态发生蛋白-2（rhBMP-2）结合纳米晶胶原基骨材料（nHAC）行跟骨骨折切开复位治疗时做骨塌陷缺损时填充材料，并观察其植骨治疗效果。方法：选择2008-07-2010-11 19例（21足）跟骨骨折患者，均采用跟骨外侧"L"型切口，切开复位异型钢板内固定，骨缺损处植入rhBMP-2加nHAC的混合物。结果：术后随访7~17个月，根据Maryland评分，优5足，良13足，可2足，差1足，优良率85.7%。结论：rhBMP-2结合nHAC治疗跟骨骨折是一种比较理想骨缺损填充材料。
- 跟骨骨折 /
- 重组人骨形态发生蛋白-2 /
- 纳米晶胶原基骨材料
Abstract: Objective: To investigate the clinic effect of the recombinant human bone morphogenetic protein-2 (rhBMP-2) mixed with nano-hydroxyapatite collagen (nHAC) to treat calcaneal fractures.Method: From July 2008 to November 2010, 19 patients (21 feets) with calcaneal fractures were treated by calcaneal reconstruction titanium plate assist with rhBMP-2 and nHAC.Result: All cases were followed 10 months, judge by Maryland, excellent 5 cases, good 13 cases, the good-excellent rate was 85.7%.Conclusion: rhBMP-2 mix with nHAC to treat calcaneal fractures is a ideal therapy method.
- calcaneal fractures /
- rhBMP-2 /
- nano-hydroxyapatite collagen

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